Dr D'Souza's primary research interest is in infectious causes of chronic disease. Current research explores the association between Human Papillomavirus (HPV) and oral, cervical and anal cancers, the natural history and concordance of oral and anogenital HPV infection, the use of HPV testing for screening, HPV tropism, and the epidemiology of sexually transmitted infections. Additional interests include the role of behavioral factors on viral acquisition and persistence, the effect of viral load on disease progression, the epidemiology of HIV/AIDS, and infectious causes of AIDS malignancy.

HPV, HIV, cancer, cancer etiology and prevention, AIDS malignancy, STD, sexual behavior, epidemiology, cancer screening, epidemiologic methods, high risk population, adolescents, behavior, papillomavirus 

2007 Research cited as one of top six advances in cancer research in 2007 by the American Society of Clinical Oncology (ASCO)

Click here for a full list of Dr. D'Souza's citations in PubMed

Strickler HD, Martin MP, Xue X, Burk RD, Kuniholm M, Hildesheim A, Minkoff H, Massad LS, Anastos K, Kovacs A, Fazzari M, D’Souza G, Harris T, Young M, Bonagura V, Palefsky JM, Carrington M. Informative Differences in HLA Class I/II Associations with HPV in HIV-Positive/Negative Women by Host Immune Status. Publication pending.

Minkoff H, Zhong Y, Burk R, Palefsky J, Xue X, Watts H, Levine A, Wright R, Colie C,  D’Souza G, Massad L, Strickler H. Influence and adherent and effective antiretroviral therapy use on Human Papillomavirus Infection and squamous intraepethelial lesions in HIV-positive women. JID. 2010 epub.

Marur S, D’Souza G, Westra W, Forastiere A. Epidemiology, clinical presentation and management of HPV-related head and neck cancer. Lancet Oncology. Publication Pending

D’Souza G, Palefsky J.M., Zhong Y, Minkoff H, Massad L.S., Anastos K, Levine AM, Moxley M, Xue X, Burk R, Strickler HD. Marijuana Use is Not Associated with Cervical Human Papillomavirus Natural History or Cervical Neoplasia in HIV-seropositive or HIV-seronegative Women. CEBP. Publication pending.

D’Souza G, Zhang HH, D’Souza W.D.,  Meyer R.R., Gillison M.L. Moderate predictive value of demographic and behavioral characteristics for a diagnosis of HPV16-positive and HPV16-negative head and neck cancer. Oral Onc. 2009. PMID: 20036610

Xue X, Gange S, Zhong Y, Burk R, Minkhoff M, Massad LS, Watts DH, Kuniholm M, Anastos K, Levine AM,  D’Souza G, Moxley M, Palefsky JM, Strickler HD. Marginal and Mixed Effects Models in the Analysis of HPV Natural History Data. CEBP. 2010. 19(1): 159-69. PMID: 20056635.

Goldberg D, Weber KM, Orsi J, Hessol NA, D’Souza G, Watts HD, Schwartz R, Liu C, Glesby M Burian P Cohen MH. Smoking Cessation Among Women With and At High Risk for HIV: Are They Quitting? J of General Internal Medicine. 2009. PMID: 19921113.

Massad LS, Xie, Darragh T, Levine A, D’Souza G, Cajigas A, Minkoff H, Colie C, Watts H, Strickler H. Histologic correlates of glandular abnormalities in cervical cytology. Obstetrics & Gynecology. 2009. 114: 1063-8.

Adelstein DJ, Ridge JA, Gillison ML., Chaturvedi AK, D’Souza G, Gravitt PE Westra W, Psyrri A, Kast WM Koutsky LA, Giuliano A, Krosnick S, Trotti A, Schuller DE, Forastiere ,A Ullmann CD. Squamous Cell Head and Neck Cancer and the Human Papillomavirus: Summary of a State of the Science Meeting, November 9-10, 2008, Washington, D.C. Head and Neck. 2009. 31 (11): 1393-1422. PMID: 19787782.

D’Souza W, Malinowski K, Van Liew S., D’Souza G, Asbury K, McAvoy TJ, Suntharalingam M, Refine WF. Investigation of motion sickness and inertial stability on a moving couch for intra-fraction compensation. Acta Oncologica. 2009 Aug 27: 1-7. PMID: 19863229.

D’Souza G, Agrawal Y, Halpern J, Bodison S, Gillison ML. Oral sexual behaviors associated with prevalent oral human papillomavirus (HPV) infection. JID. 2009. 199(9):1263-1269. PMID: 19320589. [Commentary accompanying this article PMID: 19320591].

D’Souza G, Cook RL, Ostrow D, Johnson-Hill LM, Wiley D, Silvestre T. Anal cancer screening behaviors and intentions in men who have sex with men. J of General Internal Medicine. 2008. 23(9):1452-7. PMID: 18618198.

D’Souza G, Wiley D, Li X, Chmiel JS, Margolick J, Cranston RD, Jacobson L. Incidence and epidemiology of anal cancer in the Multicenter AIDS Cohort Study. J Acquir Immune Defic Syndr. 2008;48(4): 491-499. PMID: 18614927.

Massad LS, Evans CT, D’Souza G, Darragh T, Minkhoff H, Henry D, Goparaju L, Muderspacj LI, Watts HD. High-grade cervical disease in adolescents with HIV. J of Lower Genital Tract Dis. 2008. 12(3): 199-203. PMID: 18596461.

Minkhoff H, Zhong Y, Strickler HD, Watts DH, Palefsky JM, Levine A, D’Souza G, Howard AA, Plankey M, Massad LS, Burk R. The relationship between cocaine use and human papillomavirus infections in HIV-seropositive and HIV-seronegative women. Infectious Diseases in Obstetrics and Gynecology. 2008. Article ID 587082. PMID: 18437233.

Gillison ML, D’Souza G, Westra W, Sugar E, Xiao W, Begum S, Viscidi R. Distinct risk factor profiles for HPV-positive and HPV-negative head and neck squamous cell carcinoma. JNCI. 2008. 100 (6); 407-20. PMID: 18334711.

D’Souza G, Fakhry C, Sugar E, Seaberg E, Weber K, Minkoff H, Anastos K, Palefsky J, Gillison M. Six-month natural history of oral versus cervical human papillomavirus infection. Int J Cancer. 2007 Jul 1;121(1):2897-904. PMID: 17354235.

D’Souza G, Kreimer AR, Viscidi R, Pawlita M, Fakhry C, Koch W, Westra W, Gillison ML. Case-control study Human Papillomavirus and Oropharyngeal Squamous Cell Carcinoma. New England Journal of Medicine. 2007. 356: 1944-56. PMID: 17494927.

Fakhry C, D’Souza G, Sugar E, Weber K, Goshu E, Minkhoff H, Wright R, Seaberg E, Gillison M. The relationship between prevalent oral and cervical HPV infections in HIV-positive and negative women. Journal of Clinical Virology. 2006. 44(12): 4479-4485. PMID: 17021055.

D’Souza G, Sugar E, Ruby W, Gravitt P, Gillison M. Analysis of the effect of DNA purification on detection of human papillomavirus in oral rinse samples by PCR. Journal of Clinical Virology. 2005. 43(11):5526-35. PMID: 16272481.

D’Souza G, Lee L and Paffel J.  Outbreak of early syphilis in men who have sex with men in Houston. Sex Trans Dis. 2003. 30(12): 872-873. PMID: 14646631.

D’Souza G, Arafat R, Hwang L, Cunningham C, Shah S, and Reynolds K.  Cross sectional study of the extent and indicators of hepatitis C virus infection in Houston.  Journal of Viral.  2003 Mar; 10(2):134-140. PMID: 12614470.

Waring DC, Reynolds KM, D’Souza G, and Arafat RR.  Rapid assessment of household needs in the Houston area after tropical storm Allison. Disaster Manage Response 2002: 1:3-9.  PMID: 12685459.