Dr. MacKenzie's research focuses on the impact of health services and policies on the short-and long-term consequences of traumatic injury. She has contributed to the development and evaluation of tools for measuring both the severity and outcome of injury, which have been used to evaluate the organization, financing and performance of trauma systems and rehabilitation services . Of particular interest to Dr. MacKenzie is the delineation of factors (both medical and non-medical) that explain variations in functional outcome. Her research has advanced the knowledge of the economic and social impact of injuries and our understanding of how personal and environmental factors influence recovery and return to work.

Dr. MacKenzie's ongoing research include: a national evaluation of the cost and effectiveness of trauma care; the evaluation of amputation versus limb salvage in the military; the development and evaluation of self management programs following trauma and limb loss; and efforts to facilitate the development and exchange of information among trauma and EMS providers. Most recently, Dr. MacKenzie and colleagues have partnered with the American Trauma Society to facilitate on-line social networks among trauma survivors and translate traditional self management programs to a web 2.0 environment.

injury control, outcomes research, disability and rehabilitation, health services reserach, consumer informatics

Phi Beta Kappa Golden Apple for Teaching, Johns Hopkins School of Hygiene and Public Health, 1984 Delta Omega, Public Health Honorary General Motors Trauma Research Award, Eastern Association for the Surgery of Trauma A.J. Mirkin Service Award, Association for the Advancement of Automotive Medicine Charter Fellow, Association for the Advancement of Automotive Medicine Honorary Fellow, American Association for the Surgery of Trauma Distinguished Career Award, American Public Health Association (Injury Control and Emergency Health Services Section) Distinguished Achievement Award, American Trauma Society Award of Merit, Association for the Advancement of Automotive Medicine Ann Doner Vaughan Kappa Delta Award, American Academy of Orthopaedic Surgeons Nursing Leadership Award, Society of Trauma Nurses President, American Trauma Society

Rivara FP, MacKenzie EJ, Jurkovich GJ, Nathens AN, Wang J, Scharfstein DO. Prevalence of pain in patients one year following major trauma. Archives of Surgery. 2008;143(3):282-7; discussion 288.

Ziegler-Graham K, MacKenzie EJ, Travison TG, Ephraim PL, Brookmeyer R. Estimating the Prevalence of Limb Loss in the United States: 2005 – 2050. Archives of Physical Medicine and Rehabilitation, 2008 Mar; 89(3):422-9.

MacKenzie EJ, Rivara FP, Nathens AN et al. Impact of Trauma Center Care on One-Year Functional Outcomes. Journal of Bone and Joint Surgery. 2008; 90:101-109.

Efron DT, Sorock G, Haut E, Chang D, Schneider E, MacKenzie EJ, Cornwell EE, Jurkovich GJ. Pre-Injury Statin Use is Associated with Improved In-Hospital Survival in Elderly Trauma Patients. Journal of Trauma. 2008; 64(1): 66-74.

Zatzick D, Rivara F, MacKenzie EJ et al. A Nationwide U.S. Study of Posttraumatic Stress Symptoms after Hospitalization for Physical Injury. Psychological Medicine. 2007;37:1469-1480.

MacKenzie EJ, Snow-Jones A, Castillo RC, Bosse MJ and the LEAP Study Group. Direct Health Care Costs Following Amputation or Reconstruction of a Severely Injured Lower Limb. Journal of Bone and Joint Surgery. 2007; 89:1685-1692.

Frangakis CD, Rubin DB, An MW, MacKenzie EJ. Principal Stratification Designs to Estimate Input Data Missing Due to Death (with Discussions). Biometrics, 2007; 63: 641-662.

MacKenzie EJ, Rivara FP, Jurkovich GJ, Nathens AB, Frey KP, Egleston BL, Salkever DS, Weir S, Scharfstein DO. The National Study on Costs and Outcomes of Trauma. Journal of Trauma. 2007; 63(6 Suppl):S54-67; discussion S81-6.

Archer KR, Castillo RC, Mackenzie EJ, Bosse MJ. Gait symmetry and walking speed analysis following lower-extremity trauma. Physical Therapy. 2006 Dec;86(12):1630-40.

Nathens AN, Rivara FP, MacKenzie EJ, Maier RV, Wang J, Egleston B, Scharfstein DO, Jurkovich GJ. The Impact of an Intensivist-Model ICU on Trauma–Related Mortality. Annals of Surgery, 2006; 244(4):545-54.

MacKenzie EJ, Bosse MJ, Kellam JF et al. Early Predictors of Long-Term Work Disability Following Major Limb Trauma. Journal of Trauma, 2006; 61(3):688-694.

Nathens AB, Maier RV, Jurkovich GJ, Monary D, Rivara FP, MacKenzie EJ. The Delivery of Critical Care Services in US Trauma Centers: Is the Standard Being Met? Journal of Trauma. 2006 Apr;60(4):773-83; discussion 783-4.

Castillo RC, MacKenzie, Wegener ST, Bosse, and the LEAP Study Group. Prevalence of Chronic Pain Seven Years Following Limb Threatening Lower Extremity Trauma. Pain, 2006; 124:321-329.

MacKenzie EJ, Rivara FP, Jurkovich GJ, Nathens AN et al. A National Evaluation of the Effect of Trauma-Center Care on Mortality. New England Journal of Medicine, 2006; Jan 26;354(4):366-78.

McCarthy ML, MacKenzie EJ, Durbin DR, Aitken ME, Jaffe KM, Paidas CN, et al. Health-Related Quality of Life During the First Year Post Traumatic Brain Injury. Archives of Pediatrics and Adolescent Medicine. 2006; 160:252-260.

MacKenzie EJ, Bosse MJ, Pollak AN et al. Disability Persists Long –Term Following Severe Lower Limb Trauma: Results of a Seven Year Follow-up. Journal of Bone and Joint Surgery, 2005; 87(8):1801-9.

Branas CC, MacKenzie EJ, Williams JC, Schwab CW, Teter HM, Flanigan MC, Blatt AJ, ReVelle CS. Access to Trauma Centers in the United States. JAMA, 2005; 293(21): 2626-2633.

McCarthy ML, MacKenzie EJ, Durbin DR, Aitken ME, Jaffe KM, Paidas CN, et al. The Pediatric Quality of Life Inventory (PedsQL TM 4.0): an evaluation of its psychometric characteristics for children with traumatic brain injury. Archives of Physical Medicine and Rehabilitation, 2005; 86(10): 1901-1909.

MacKenzie EJ, Bosse MJ, Castillo RC, Smith DG et al., Functional Outcomes Following Lower Extremity Amputation for Trauma. Journal of Bone and Joint Surgery, 2004; 86-A(8):1636-45.

Nathens AB, Jurkovich GJ, MacKenzie EJ, Rivara FP. Resource-based Assessment of Trauma Care in the United States. Journal of Trauma, 2004; 56(1):173-178.

MacKenzie EJ, Bosse MJ, Castillo RC, Smith DG et al. Functional Outcomes Following Lower Extremity Amputation for Trauma. Journal of Bone and Joint Surgery, 2004; 86-A(8):1636-45

MacKenzie EJ, Hoyt DB, Sacra JC, Jurkovich GJ, Carlini AR, Teitelbaum SD, Teter H. A National Inventory of Hospital Trauma Centers. JAMA. 2003; 289: 1515-1522.

McCarthy ML, MacKenzie EJ, Edwin D, Bosse MJ, Castillo RC, Starr A and the LEAP Study Group. Psychological Distress Associated with Severe Lower Limb Injury. Journal of Bone and Joint Surgery, 2003; 85-A (9): 1689-97.

Bosse MJ, MacKenzie EJ, Kellam JF, et al. Reconstruction or Amputation of Lower Limb Threatening Injuries: An Analysis of Two-Year Outcomes in Level I Trauma Centers. New England Journal of Medicine, 2002; 347(24): 1924-1931.

MacKenzie EJ, McCarthy ML, Luchter S, Ditunno JF, Forrester-Staz C, Gruen GS, Marion DW, Schwab CW and the Pennsylvania Trauma Study Group. Validating the Functional Capacity Index. Quality of Life Research, 2002; 11(8): 797-808.