my.jhsph.edu   Home Admissions Academics Departments Research & Centers Practice
Faculty
DIRECTORIES
Faculty Directory

EPI Faculty Directory


GLOBAL PROJECTS
Global Projects Map

EPI Project Map

TOOLS
Contact JHSPH
Feedback

Email this Page
Calendar
Course Search
Faculty
Nathan Wolfe
Professor
- Adjunct
Academic Degrees
ScD
Departmental Affiliation
Epidemiology
Infectious Disease Epidemiology
Joint Departmental Affiliations
Molecular Microbiology and Immunology and
International Health
Departmental Address
Current Position: Lokey Visiting Professor at Stanford University
Stanford email address: ndwolfe@stanford.edu
Website: www.gvfi.org
Phone: Asst Lucy: (310) 592-7144
Fax: (800) 724-1706
Research and Professional Experience

Most human viruses originated from wild animal populations (e.g. HIV, influenza, dengue, SARS, ebola, etc). My lab is working to identify the factors which allow viruses to cross from animals into humans and to develop systems to monitor the emergence of viruses before they reach epidemic levels.

Current projects include: 1) Hunter cohort study: monitor viruses among hunters living in and around biodiversity hotspots 2) Animal health study: catalog viruses in hunted animals and survey for wild animal ‘die-offs’ 3) Virus diversity study: characterize previously unknown viruses in human & animal populations 4) Rural health development project: provision of technical assistance and resources to aid in the development of local health infrastructure for provision of prevention and care for HIV and other infectious diseases

These projects are supported by laboratory and repository facilities in the USA and overseas laboratory sites

Keywords

bushmeat, AIDS, zoonosis, molecular epidemiology, pathogen ecology and evolution, cross-species transmission, primatology, Cameroon, Central Africa, phylogenetics, GIS, international health, RNA virus, evolution, retrovirus, arbovirus, filovirus, monkeypox, malaria, ebola, lassa, marburg, dengue, yellow fever, leptospirosis, rabies, spumaretrovirus, simian foamy virus (SFV), SIV, HIV, STLV, HTLV, hepatitis

Honors and Awards

NIH Director's Pioneer Award, 2005-2010

Popular Science "Brilliant 10", 2005

International Research Scientist Development Award (IRSDA), NIH Fogarty International Center, 1999-2006

Fulbright Fellowship, 1997-1998

National Science Foundation Graduate Research Fellowship, 1994-1997

Certificate of Distinction for Teaching, Harvard University, 1994

Selected Publications

&backto

Sintasath DM, Wolfe ND, Lebreton M, Jia H, Garcia AD, Le Doux-Diffo J, Tamoufe U, Carr JK, Folks TM, Mpoudi-Ngole E, Burke DS, Heneine W, Switzer W (2009 ) Simian T-lymphotropic virus diversity among nonhuman primates, Cameroon. Emerging Infectious Disease 15(2):175-84.

Switzer WM, Salemi M, Qari SH, Jia H, Gray RR, Katzourakis A, Marriott SJ, Pryor KN, Wolfe ND, Burke DS, Folks TM, Heneine W (2009) Ancient, independent evolution and distinct molecular features of the novel human T-lymphotropic virus type 4. Retrovirology 2;6:9.

ND Wolfe (2008) An epidemiologist points to a fifth sort of human malaria. Nature 453:567 [journal club]

Goldberg TL, CA Chapman, K Cameron, T Saj, WB Karesh, ND Wolfe, SW Wong, ME Dubois, MK Slifka (2008) Serologic evidence for a novel poxvirus in endangered red colobus monkeys, Western Uganda. Emerging Infectious Disease 14: 801-803

Wolfe ND†, C Panosian Dunavan, J Diamond (2007) Origins of major human infectious diseases. Nature 447:279-283

LeBreton M, Umlauf S, Djoko CF, Daszak P, Burke DS, Kwenkam PY, Wolfe ND (2006) Rift Valley Fever in Goats, Cameroon Emerging Infectious Disease, April 2006; 12(4): 702-703. http://www.cdc.gov/ncidod/EID/vol12no04/pdfs/05-1428.pdf

Wolfe ND, P Daszak, AM Kilpatrick, DS Burke (2005) Bushmeat hunting, deforestation, and predicting zoonotic emergence. Emerging Infectious Diseases (in press)

Zhang M, K Wilbe, B Gaschen, ND Wolfe, B Gaschen, J Carr, T Leitner (2005) HIV-1 CRF13-cpx revisited: identification of a new sequence from Cameroon and signal for sub-subtype J2. AIDS Research & Human Retroviruses (in press) Cummings AT, WJ Moss, K Long, TJ Muluh, B Kollo, E Nomo, ND Wolfe, DS Burke (2005) Improved measles surveillance in Cameroon reveals two major dynamic patterns of incidence. International Journal of Infectious Disease (in press)

N. D. Wolfe, W. Heneine, J. K. Carr, A. D. Garcia, V. Shanmugam, U. Tamoufe, J. N. Torimiro, A. T. Prosser, M. LeBreton, E. Mpoudi-Ngole, F. E. McCutchan, D. L. Birx, T. M. Folks, D. S. Burke, and W. M. Switzer. 2005 Emergence of unique primate T-lymphotropic viruses among central African bushmeat hunters PNAS, May 31, 2005; 102(22): 7994 - 7999. 102:7994-7999

Machuca A, O Wood, S Lee, S Daniel, M Rios, ND Wolfe, J Carr, E Mpoudi-Ngole, D Burke, I Hewlett (2005) Seroprevalence of HTLV in HIV antibody negative populations of rural Cameroon. Clinical Infectious Disease 40:1673-6

Carr JK, Y Nadai, L Eyzaguirre, MD Saad, MM Khakimov, SK Yakubov, DL Birx, RR Graham, ND Wolfe, KC Earhart, JL Sanchez (2005) Outbreak of a west African recombinant of HIV-1 in Tashkent, Uzbekistan. Journal of Acquired Immune Deficiency Syndromes 39:570-575

Wolfe ND, WM Switzer, JK Carr, VB Bhullar, V Shanmugam, U Tamoufe, AT Prosser, JN Torimiro, A Wright, E Mpoudi-Ngole, FE McCutchan, DL Birx, TM Folks, DS Burke, W Heneine (2004) Naturally acquired simian retrovirus infections among Central African hunters. Lancet 363:932-37 (also see commentary: 363:911-912; and letters: 364:137-140)

Wolfe ND, AT Prosser, JK Carr, U Tamoufe, E Mpoudi-Ngole, JN Torimiro, M LeBreton, FE McCutchan, DL Birx, DS Burke (2004) Exposure to nonhuman primates in rural Cameroon. Emerging Infectious Diseases 10:2094-99

Waters H, L Dougherty, N Tran, S Charles, SP Tegang, K Long, ND Wolfe, DS Burke (2004) Coverage and costs of childhood immunizations in Cameroon. Bulletin of the World Health Organization 82:668-75

Patz J, P Daszak, AA Aguirre, GM Tabor, M Pearl, J Epstein, ND Wolfe, J Foufopoulos, D Molyneux, DJ Bradley, and Members of the Working Group on Unhealthy Landscapes (2004) Unhealthy landscapes: policy recommendations pertaining to land use change and disease emergence. Environmental Health Perspectives 112:1092-8 Kijak GH, E Sanders-Buell, ND Wolfe, E Mpoudi-Ngole, B Kim, ML Robb, DL Birx, DS Burke, JK Carr, FE McCutchan (2004) Development and application of a high-throughput HIV-1 genotyping assay to identify CRF02_AG in West/West Central Africa. AIDS Research & Human Retroviruses 20:521-30

Hussain AI, V Shanmugam, VB Bhullar, BE Beer, D Vallet, A Gautier-Hion, ND Wolfe, WB Karesh, AM Kilbourn, Z Tooze, W Heneine, WM Switzer (2003) Screening for simian foamy virus infection by using a combined antigen western blot assay: Evidence for a wide distribution among old world primates and identification of four new divergent viruses. Virology 309:248-257

Wolfe ND, WB Karesh, AM Kilbourn, J Cox-Singh, EJ Bosi, HA Rahman, B Singh, M Andau, A Spielman (2002). The impact of ecological conditions on the prevalence of malaria among orangutans. Vector Borne & Zoonotic Disease 2:97-104

Patz J & ND Wolfe (2002) Global ecological change and human health. In: Conservation Medicine: Ecological Health in Practice (eds. AA Aguirre, RS Ostfeld, GM Tabor, C House, and MC Pearl), pp. 167-181. Oxford University Press, Oxford

Deem SL, AM Kilbourn, ND Wolfe, RA Cook, WB Karesh (2002) Conservation medicine. Annals of the New York Academy of Sciences 916:370-377

Carr JK, JN Torimiro, ND Wolfe, MN Eitel, B Kim, E Sanders-Buell, LL Jagodzinski, D Gotte, DS Burke, DL Birx, FE McCutchan (2001) The recombinant IbNG and novel strains of group M HIV-1 are common in Cameroon. Virology 286:168-181

Wolfe ND, AM Kilbourn, WB Karesh, HA Rahman, EJ Bosi, BC Cropp, M Andau, A Spielman, DJ Gubler (2001) Sylvatic transmission of arboviruses among Bornean orangutans. American Journal of Tropical Medicine and Hygiene 64:310-316

Wolfe ND, MN Eitel, J Gockowski, PK Muchaal, C Nolte, AT Prosser, JN Torimiro, SF Weise, DS Burke (2000) Deforestation, hunting and the ecology of microbial emergence. Global Change and Human Health 1:10-25

Wrangham R. M Wilson, B Hare, ND Wolfe (2000) Chimpanzee predation and the ecology of microbial exchange. Microbial Ecology in Health and Disease 12:186-188

Wolfe ND, AA Escalante, WB Karesh, AM Kilbourn, A Spielman, & AA Lal (1998) Wild primate populations in emerging infectious disease research. Emerging Infectious Disease 4:149-158

Nathan Wolfe Photo
© , Johns Hopkins University. All rights reserved.
Web policies, 615 N. Wolfe Street, Baltimore, MD 21205