Dr. Astor’s research is focused on the interaction between kidney disease and cardiovascular disease, and their impact on the population. His research involves cohort studies of individuals with kidney failure (e.g., Choices for Healthy Outcomes in Caring for ESRD [CHOICE] Study), individuals with chronic kidney disease (e.g., Chronic Renal Insufficiency Cohort [CRIC] Study), and the general population (e.g., Atherosclerosis Risk in Communities [ARIC] Study), as well as utilizing publicly available datasets (e.g., National Health and Nutrition Examination Survey [NHANES]). These studies are undertaken in an attempt to better understand the connection between kidney disease and cardiovascular disease in the population, and identify areas of intervention to minimize the burden of these diseases.

cardiovascular, kidney, anemia, dialysis, vascular access

Jean Coombs Award for Student Research in Epidemiology, 1999

Delta Omega Public Health Honorary Society Alpha Chapter Scholarship, 1999

Mary B. Meyer Award, 1999

Charlotte Silverman Fellowship, 2000

Harry and Jeanette Weinberg Endowment Cardiovascular Research Award, 2000

Astor BC, Arnett DK, Brown A, Coresh J. Association of kidney function and hemoglobin with left ventricular morphology among African Americans: The Atherosclerosis Risk in Communities (ARIC) Study. Am J Kidney Dis (in press)

Christopher-Stine L, Petri M, Astor BC, Fine D. Urine protein-to-creatinine ratio is a reliable measure of proteinuria in lupus nephritis. J Rheum (in press)

Eustace JA, Astor BC, Muntner PM, Ikizler TA, Coresh J. Inflammation and acidosis are independently associated with hypoalbuminemia across the spectrum of reduced glomerular filtration rates within the US population. Kidney Int 2004;65:1031-1040

Jaar BG, Astor BC, Berns JS, Powe NR. Predictors of lower extremity amputation and survival of hemodialysis patients following revascularization for peripheral vascular disease. Kidney Int 2004;65:613-620

Coresh J, Astor BC, Sarnak MJ. Evidence for increased cardiovascular disease risk in patients with chronic kidney disease. Curr Opin Nephrol Hypertens 2004;13:73-81

Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS. Prevalence of chronic kidney disease in the adult US population: Third National Health and Nutrition Examination Survey. Am J Kidney Dis 2002;41:1-12

Kovesdy CP, Astor BC, Longenecker JC, Coresh J. Association of kidney function with serum lipoprotein(a) level: the Third National Health and Nutrition Examination Survey (1991-1994). Am J Kidney Dis 2002;40:899-908

Astor BC, Muntner M, Levin A, Eustace JA, Coresh J. Association of kidney function with anemia: the Third National Health and Nutrition Examination Survey (1988-1994). Arch Intern Med 2002;162:1401-1408

Coresh J, Astor BC, McQuillan G, Kusek J, Greene T, Van Lente F, Levey AS. Calibration and random variation of the serum creatinine assay as critical elements of using equations to estimate glomerular filtration rate. Am J Kidney Dis 2002;39:920-929

Astor BC, Eustace JA, Klag MJ, Powe NR, Longenecker JC, Fink NE, Marcovina SM, Coresh J. Race-specific association of lipoprotein(a) with vascular access interventions in incident hemodialysis patients: the CHOICE Study. Kidney Int 2002;61:1115-1123

Astor BC, Eustace JA, Powe NR, Klag MJ, Sadler J, Fink NE, Coresh J. Timing of nephrologist referral and arteriovenous access use: the CHOICE Study. Am J Kidney Dis 2001;38:494-501

Horvath KA, Astor BC. On clinical trials for TMLR. Cardiac Vasc Regeneration 2000;1:144

Astor BC, Kaczmarek RG, Hefflin B, Daley WR. In-hospital mortality following aortic valve replacement: results from a nationally representative study. Ann Thorac Surg 2000;70:1939-1945.

Astor BC, Coresh J, Powe NR, Eustace JA, Klag MJ. Relation between gender and vascular access complications in hemodialysis patients. Am J Kidney Dis 2000;36:1126-1134.

Book Chapters

Shatin D, Bright RA, Astor BC. Databases for studying the epidemiology of implanted medical devices. In: Johnson FE, Virgo KS, editors. The Bionic Patient. St. Louis: Mosby (in press, 2004)

ARIC Study

ARIC Carotid MRI Study

MESA Air Study

bastor@jhsph.edu