Personal objectives

To contribute to population health through quantitative and qualitative research in health sciences and through evidence-based contributions to real-life policy making.

Topics

1. Health policy for population health: priority setting, allocative efficiency, reimbursement, evidence-based practice guidelines, public health programs.

2. Data-driven integrated modeling of population health: lifetime health and cost of interventions related to heart disease, stroke, diabetes, chest disease, malaria, pneumonia, hepatitis in health systems research & health impact & reproduction assessments.

3. Real-life cluster-trial impact assessment of (system) interventions in chronic and other diseases; combined with model-based extrapolation and standardisation.

Health systems, health economics, epidemiological modeling, health services research, health policy research, reimbursement decisions, professional medical guidelines, implementation trials, developing and developed countries. UN-agencies and country experiences: W-Europe, Peru (Amazon, Altiplano), NW Tanzania, S-Africa, Nepal (Terrai, Himal), India, and Cambodia.

-Founder Member, Netherlands Platform Global Health Policy & Health Systems Research; Scientific Commitees, IHEA and ECHE Conferences, 2006-now; Former Chair, Dutch Society Tropical Medicine & International Health; Vice-Chair 5th European Conference Tropical Medicine & International Health; Erasmus Medical School Board & Executive Board.

Wijngaarden J*, Dirks M*, Fabricotti I, Huijsman R, Niessen LW, Dippel D: Hospital rates of thrombolysis for acute ischaemic stroke; the influence of organizational culture. Stroke, 2009. In press.

Cleveringa FGW*, Welsing PMJ, Donk van den M, Gorter KJ, Niessen LW et al.: Cost-effectiveness of the Diabetes Care Protocol, a multifaceted computerized decision support diabetes management intervention that reduces cardiovascular risk’, Diabetes Care, 2009. Accepted.

Niessen LW, Hove ten AC*, Hilderink HH, Weber M, Mulholland K, Ezzati M. Comparative impact assessment of child pneumonia interventions. Bull WHO, 2009 Jun;87(6):472-8.

Cobden DB*, Niessen LW, Barr CE, Rutten F, Redekop WK. Relationships among self-management, patient perceptions of care, and health economic outcomes for decision-making and clinical practice in type 2 diabetes. Value in Health, 2009, Aug 20. [Epub ahead of print].

Heijden vd A*, Ortegon M*, Niessen LW, Nijpels G, Dekker, JM. Prediction of coronary heart disease in a general, pre-diabetic and diabetic population during 10 years of follow-up: accuracy of the Framingham, SCORE and UKPDS risk functions - the Hoorn Study. Diabetes Care, 2009. In press.

Bosch M*, Weijden van der T, Grol R, Schers H, Niessen LW, Wensing M: Structured primary care and health-related quality of life in chronic heart failure. BMC Health Services Research, 2009 Jun 19;9:104.

Jansink R*, Braspenning J, Weijden van der T, Niessen L, Elwyn G, Grol R. Nurse-led motivational interviewing to change the lifestyle of patients with type 2 diabetes (MILD-project): protocol for a cluster, randomized, controlled trial on implementing lifestyle recommendations. BMC Health Serv Res. 2009 30;9-19.

Redekop WK, Orlewska E, Maciejewski P, Rutten FH, Niessen LW. Costs and effects of secondary prevention with perindopril in stable coronary heart disease in Poland - an analysis of the EUROPA Study including 1251 Polish patients. Pharmacoeconomics. 2008; 26 861-77.

Bhatta N*, Dhakal SS, Rizal S, Kralingen KW, Niessen L. Clinical spectrum of patients presenting with bronchiectasis in Nepal: evidence of linkage between tuberculosis, tobacco smoking and toxic exposure to biomass smoke. Kathmandu Univ Med J (KUMJ). 2008 Apr-Jun;6(2):195-203.

Baltussen R, Asbroek AHA*, Shrestha N*, Bhattharai P* and Niessen LW. A rational multi-criteria approach to priority setting: should a lung health programme be implemented in Nepal? Health Pol Plan 2007; 22(3):178-85.

Bont de A, Zandwijken G*, Stolk E, Niessen L. Prioritisation by physicians in the Netherlands--the growth hormone example in drug reimbursement decisions. Health Policy. 2007; 80(3):369-77.

Dirks M*, Niessen LW, Koudstaal PJ, Franke C, van Oostenbrugge RJ, Dippel DWJ: IV thrombolysis in acute ischemic stroke. from trial to clinical indications- an international Delphi study. J Neur Neurs Psych 2007;78:685-9

Dirks M*, Niessen LW, Koudstaal PJ, and Dippel DWJ: Promoting acute thrombolysis for ischaemic stroke (PRACTISE) A cluster randomised controlled trial (ISRCTN 20405426). Int J Stroke. 2007; 2(2):151-9.

Gravelle H, Brouwer W, Niessen LW, Postma P and Rutten FFH: Discounting in economic evaluations: stepping forward towards optimal decision rules. Health Economics 2007;16:307-17.

Niessen LW, Grijseels E, Koopmanschap M and Rutten FFH: Economic evidence for clinical practice – the case of 31 Dutch consensus guidelines. J Eval Clin Pract. 2007; 13(1):68-78.

Niezen M*, de Bont A, Stolk E, Eyck A, Niessen L, Stoevelaar H. Conditional reimbursement within the Dutch drug policy. Health Policy. 2007;84:39-50.

Baltussen R and Niessen LW: Priority setting of health interventions: The need for multi-criteria decision analysis. CERA, 2006; 4:14.

Dijkstra RF*, Niessen LW, Braspenning JC, Adang E, Grol RT. Patient-centred and professional-directed implementation strategies for diabetes guidelines: a cluster-randomized trial-based cost-effectiveness analysis. Diabet Med. 2006;23:164-70.

Etten van G, Baltussen R, Bijlmakers L, Niessen L: Advancing the Mexico agenda for health systems research - from clinical efficacy to population health. Trop Med Int Health. 2006;11:1145-6.

Shrestha N*, Samir KC*, Baltussen R, Kafle KK, Bishai D, Niessen L. Practical approach to lung health in Nepal: better prescribing and reduction of cost. Trop Med Int Health. 2006;11:765-72.

Wijngaarden van JD*, Dirks M*, Dippel DW, Minkman M*, Niessen LW. Towards effective and efficient care pathways: thrombolysis in acute ischemic stroke. QJM. 2006; 99(4):267-72.

Asbroek ten AH*, Delnoij DM, Niessen LW, Scherpbier RW, Shrestha N* et al.: Implementing global knowledge in local practice: a WHO lung health initiative in Nepal. Health Pol Plan, 2005; 20(5):290-301.

Baltussen R, Brouwer W, Niessen L. Cost-effectiveness analysis for priority setting in health: penny-wise but pound-foolish. Int J Technol Assess Health Care. 2005;21:532-4.

Brouwer WB, Niessen LW, Postma MJ and Rutten FFH: Need for differential discounting of costs and health effects in cost effectiveness analyses. BMJ 2005;331:446-8.

Exel van NJ*, MA Koopmanschap, W Scholte, R Huijsman, LW Niessen: Cost effectiveness of integrated stroke services: a prospective study in 411 Dutch patients. QJM – Int J Med 2005; 98(6):415-25.

Hutubessy R*, Niessen LW Dijkstra R*, Casparie AF, Rutten FFH: Stochastic league tables for diabetes treatment in The Netherlands. Health Econ, 2005; 14(5):445-55.

Mohan CI*, Bishai D, Kumar S*, ten Asbroek G*, Niessen L: Changes in utilisation of TB health services in Nepal. Int J Tuberc Lung Dis. 2005; 9(9):1054-6.

* MSc or PhD Student