I'm interested in latent variable methods that are useful in mental health research. My dissertation will involve developing software for penalized latent class analysis, which I will use to identify latent subtypes of cognitive performance associated with APO-E.

latent variable, latent class analysis, dementia, alzheimer, quantitative taxonomy, psychiatric epidemiology

The Morton Kramer Award for the Application of Biostatistics and Epidemiology in Research on the Prevention and Control of Mental Disorders, Department of Mental Health (2005)

Ward J, Sheppard JE, Brandt J, Shpritz B, Margolis R, Rosenblatt A. A Prospective Study of Cognitive Functioning in Huntington’s Disease Over a Four-Year Follow-Up Period. In press.

Maust DT, Onyike CU, Sheppard JME, Mayer LS, Samus QM, Brandt J, Rabins PV, Lyketsos CG, Rosenblatt A. Predictors of Caregiver Unawareness and Non-treatment of Dementia among Residents of Assisted Living Facilities: The Maryland Assisted Living Study (MD-AL). Am J Ger Psychiatry. In press.

Munro CA, Brandt J, Sheppard JM, Steele CD, Samus QM, Steinberg M, Rabins PV, Lyketsos CG. Cognitive Response to Pharmacological Treatment for Depression in Alzheimer’s Disease: Results from the Depression in Alzheimer’s Study (DIADS). Am J Geriatr Psychiatry 2004, Sep-Oct;12(5):491-8.

Steinberg M, Sheppard J, Tschanz JT, Norton MC, Steffens DC, Breitner JCS, Lyketsos CG. The Incidence of Mental and Behavioral Disturbances in Dementia: The Cache County Study. J Neuropsychiat Clin Neurosci 2003, Aug;15(3):340-5.

Lyketsos CG, DelCampo L, Steinberg M, Miles-Samus Q, Steele CD, Munro C, Baker AS, Sheppard JME, Frangakis C, Brandt J, Rabins PV. Treating depression in Alzheimer’s disease: Efficacy and safety of sertraline, and the benefits of depression reduction: The DIADS Study. Arch Gen Psychiatry 2003, Jul;60(7):737-46.

Leroi I, Sheppard JME, Lyketsos CG. Cognitive Function after 11.5 Years of Alcohol Use: Relationship to Alcohol Use. Am J Epidemiol 2002, Oct 15;156(8):747-52.

Payne JL, Sheppard JE, Steinberg, M, Warren AC, Baker AS, Steele CD, Brandt J, Lyketsos CG. Incidence, Prevalence, and Outcomes of Depression in Residents of a Long-Term Care Facility with Dementia. Int J Geriatr Psychiatry 2002, 17:247-253.

Lyketsos CG, Sheppard JE, Steinberg M, Tschanz JT, Norton MC, Steffens DC, Breitner JCS. The Neuropsychiatric Disturbances of Alzheimer’s Disease Cluster Into Three Groups. Int J Geriatr Psychiatry 2001, 16(11):1043-1053.

Lyketsos CG, Sheppard JE, Steele CD, Kopunek S, Steinberg M, Baker AS, Brandt J, Rabins PV. A Randomized, Placebo-Controlled, Double-Blind, Clinical Trial of Sertraline in the Treatment of Depression

Complicating Alzheimer Disease: Initial results from the Depression in Alzheimer Disease Study. Am J Psychiatry 2000, Oct;157(10):1686-9.

Lyketsos CG, Sheppard JM, Rabins PV. Dementia in Elderly Persons in a General Hospital. Am J Psychiatry 2000 May; 157(5):704-7.