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Faculty
Patrick Breysse
Professor
Director, Division of Environmental Health Engineering, Director Industrial Hygiene Program
Academic Degrees
PhD, MHS
Departmental Affiliation
Environmental Health Sciences
Environmental Health Engineering
Departmental Address
615 N. Wolfe Street
Baltimore, MD 21205
Phone: 410.955.3608
Fax: 410.955.9334
Research and Professional Experience

Dr. Breysse is currently the Director of the Division of Environmental Health Engineering and is the Director of the ABET accredited Occupational and Environmental Hygiene Academic Program. He is also the Director the Center for Childhood Asthma in the Urban Environment. His research focuses on the evaluation and control of chemical, biological, and physical factors that can impact health or well being. In this context, Dr. Breysse's research concentrates on risk/exposure assessment. Exposure assessment research includes pollutant source characterization, exposure measurement and interpretation, development and use of biomarkers of exposure/dose/effect, and evaluating relationships between sources, exposures, doses and disease.

Dr. Breysse's research currently includes studies of indoor and outdoor air pollution and childhood asthma. He is also researching secondhand smoke exposure assessment methods using airborne and hair nicotine.

Dr. Breysse previously collaborated on a large health effects study evaluating the health impact of the 1990 Gulf War on the citizens of the Kingdom of Saudi Arabia. He has also collaborated on a follow-up study of World Trade Center clean-up workers.

Dr. Breysse co-directed a medical screening program for former Department of Energy Workers at the Los Alamos National Laboratory. This program offers screening to former atomic bomb workers based on a historical assessment of exposure to a wide variety of agents including ionizing radiation, beryllium, solvents, asbestos, lead, and noise. He is currently working on a project to extend the former workers program to Sandia National Laboratory.

Keywords

Environmental Health Sciences, industrial hygiene, exposure assessment, magnetic fields, asbestos, fiberglass, air pollution, asthma, environmental epidemiology

Honors and Awards

Meritorious Achievement Award, American Conference of Governmental Industrial Hygienists, 2006

Leader People-to People professional exchange in Occupational and Environmental Health in South Africa, 2004

Delta Omega Public Health Honorary Society inductee, 2003

Phi Beta Kappa, 1978

Selected Publications

Jones MR, Navas-Acien A, Yuan J, Breysse PN. Secondhand Smoke Concentrations in Motor Vehicles. Tobacco Control, doi:10.1136/tc.2009.029942 (2009).

Wang T, Chiang ET, Moreno-Vinasco L, Lang GD, Pendyala S, Samet JM, Geyh AS, Breysse PN, Garcia JG. Particulate Matter Disrupts Human Lung Endothelia Barrier Integrity via ROS- and p38 MAPK-Dependent Pathways. Am J Respir Cell Mol Biol, doi:10.1165/rcmb.2008-0402OC (2009).

Bautista LE, Correa A, Baumgartner J, Breysse P, Matanoski GM. Indoor Charcoal Smoke Exposure and Acute Respiratory Tract Infections in Young Children in the Dominican Republic. Am J Epidmiol, 169(5):572-80 (2009).

Zhao Y, Usatyuk PV, Gorshkova IA, He D, Wang T, Moreno-Vinasco L, Geyh AS, Breysse PN, Samet JM, Spannhake EW, Garcia JG, Natarajan V. Regulation of COX-2 Expression and IL-6 Release by Particulate Matter in Airway Epithelial Cells. Am J Respir Cell Mol Biol, 40(1):19-30 (2009).

McCormack MC, Breysse PN, Matsui EC, Hansel NN, Williams D, Curtin-Brosnan J, Eggleston P, GB Diette. In-Home Particle Concentrations and Childhood Asthma Morbidity. Env Health Perspectives, 117(2):294-8 (2009).

Kim SR, Wipfli H, Tang E, Samet JM, Breysse PN. Method Validation for Measurement of Hair Nicotine Level in Nonsmokers. Biomedical Chromatography, 23(3):273-9 (2009).

Hansel NN, Breysse P, McCormack MC, Matsui EC, Curtin-Brosnin J, Williams DL, Moore JL, Cuhran JL, Diette GB. A Longitudinal Study of Indoor Nitrogen Dioxide Levels and Asthma Symptoms in Inner City Children. Env Health Perspectives, 116(10):1428-32 (2008).

Williams MA, Rangasamy T, Bauer SM, Killedar S, Karp M, Kensler TW, Yamamoto M, Breysse P, Biswal S, Steve N. Georas Disruption of the Transcription Factor Nrf2 Promotes Pro-Oxidative Dendritic Cells That Stimulate Th2-Like Immunoresponsiveness upon Activation by Ambient Particulate Matter. J Immunol, 181(7): 4545-4559 (2008).

Wang T, Moreno-Vinasco L, Huang, Y, Lang GD, Linares JD, Goonewardena SN, Grabavoy A, Samet JM, Geyh AS, Breysse PN, Lussier YA, Natarajan V, Garcia JGN. Murine Lung Responses to Ambient Particulate Matter: Genomic Analysis and Influence on Airway Hyperresponsiveness. Env Health Perspectives, 116(11)1500-8 (2008).

Kim S, Aung T, Berkeley E, Diette GB, Breysse PN: Measurement of Nicotine in Household Dust. Env Res, 108:289-293 (2008).

Curtin-Brosnan J, Matsui MC, Breysse P, Hansel NH, Tonorezos ES, McCormack MC, Eggleston PA, Diette GB. Parent Report of Pests and Pets and Indoor Allergen Levels in Inner City Homes. Annals of Allergy, Asthma, & Immunology, 101(5):517-23 (2008).

De Castro BR, Buckley TJ, Wang L, Mihalic JN, Breysse PN, Geyh AS. The Longitudinal Dependence of Black Carbon Concentration on Traffic Volume in an Urban Environment

J Air & Waste Manage Assoc, 58:928-939 (2008).

White RH, Stineman CH, Symons JM, Breysse PN, Kim SR, Bell ML, Samet JM. Premature mortality in the Kingdom of Saudi Arabia associated with particulate matter air pollution from the 1991 Gulf War. Human and Ecological Risk Assessment, 14(4): 645-664 (2008).

Matsui EC, Hansel NH, McCormack MC, Rusher R, Breysse PN, Diette GB. Asthma in the Inner City and the Indoor Environment. Immunology and Allergy Clinics of North America, 28(3):665-86 (2008).

Diette GB, McCormack MC, Hansel NH, Breysse PN, Matsui EC. Environmental Issues in Managing Asthma. Respiratory Care, 53(5):602-17 (2008).

Wipfli H, Avila-Tang E, Navas-Acien A, Onicescu G, Kim SR, Yuan J, Breysse PN, Samet JM and the FAMRI Homes Study Investigators. Exposure to Secondhand Smoke among Women and Children Worldwide. American Journal of Public Health, 98(4):672-9 (2008).

McCormack M, Breysse PN, Hansel NN, Matsui EC, Tonorezos ES, Curtin-Brosnan J, Williams DL, Buckley TJ, Eggleston PA, Diette GB. Common Household Activities are Associated with Elevated Particulate Matter Concentrations in Bedrooms of Inner-City Baltimore Pre-School Children. Environmental Research. 106(2):148-55 (2008).

Tonorezos ES, Breysse PN, Eggleston PA, Matsui EC, Curtin-Brosnan J, McCormack M, Hansel N, Diette GB: Does Neighborhood Violence Lead to Depression? Social Science and Medicine, 67(1):31-7 (2008).

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